Cellular Cleanup


Researchers in UC Santa Barbara neuroscientist Kenneth S. Kosik’s(link is external) lab have discovered a novel organelle — a previously unknown cell structure whose function it is to help clean up faulty proteins in times of stress and keep cells functioning in top condition. Optimizing this membraneless organelle, which they call a BAG2 condensate, could lead to treatments for conditions that are the result of misfolded proteins, including Alzheimer’s disease, Parkinson’s disease and other neurodegenerative conditions. Their results are reported in a paper(link is external) led by project scientist Daniel C. Carrettiero(link is external) and published in the journal Nature Communications.

News Date: 

Thursday, June 16, 2022